PEER-REVIEWED PAPER SUGGESTS IN-SILICO ANALYSIS & IN-VIVO RESULTS CONCUR ON GLUTATHIONE DEPLETION IN GLYPHOSATE RESISTANT GMO SOY
A recent study published in the peer-reviewed journal American Journal of Plant Sciences predicted a nearly 400% difference in glutathione oxidation as measured by the ratio of GSH and GSSG, in RRS that are glyphosate-treated glyphosate-resistant Soy versus the Organic Soy. These predictions also concur with in vivo greenhouse results. This concurrence suggests these in silico models of C1 metabolism may provide a viable and validated platform for biosafety assessment of GMOs, and aid in selecting rational criteria for informing in vitro and in vivo efforts to more accurately decide in the problem formulation phase which parameters need to be assessed so that conclusion on “substantial equivalence” or material difference of a GMO and its non-GMO counterpart can be drawn on a well-grounded basis.
The study is an outcome of four previous scientific papers, published in AGRICULTURAL SCIENCES and THE AMERICAN JOURNAL OF PLANT SCIENCES.